Kamalini has a great passion for theatre and landed in Mumbai from Kolkata for a course in the same.

In between she took up some modelling assignments when she got her break with Phir Milenge directed by Revathy. Kamalini played Shilpa Shetty's younger sister in the film.

Soon after Kamalini was acting in South Indian films like Vettaiyaadu Vizhaiyaadu -- a Tamil film opposite Kamal Hassan, and Jalsa opposite Pawan Kalyan.