The 29-year-old American, beaten by Russia's Nadia Petrova in the second round at Roland Garros at the end of May, is recovering from a stress fracture in her left foot.
"Monica Seles is continuing to work with her trainer to find ways to ease the pain in her foot and will continue to do so in the hope of being competitive for the U.S. Open," a spokesperson for her agents, IMG, told Reuters on Thursday.
Seles has been plagued by foot injuries in recent years. She suffered a stress fracture in her right foot in 2001 which kept her out for five months.
After losing to Petrova in Paris, Seles said she may quit if her injured feet did not heel.
"Yeah, it's one of the options for sure," she said. "If I'm in pain, I'm not going to be playing.
"But I'm a positive person, I try not to give up. I've faced worse stuff.
"I don't know how my body will react to rest and if it doesn't react well, then I have to stop."